ABSTRACT
The COVID-19 pandemic has caused millions of deaths and hundreds of millions of confirmed infections worldwide. This pandemic has prompted researchers to produce medications or vaccines to reduce or stop the progression and spread of this disease. A variety of previously licensed and marketed medications are being tested for the treatment and recurrence of SARS-CoV2, including favipiravir (Avigan). Favipiravir was recognized as an influenza antiviral drug in Japan in 2014, and has been known to have a potential in vitro activity against SARS-CoV-2, in addition to its broad therapeutic safety scope. Favipiravir was recently approved and officially used in many countries worldwide. Our review provides insights and up-to-date knowledge of the current role of favipiravir in the treatment of COVID-19 infection, focusing on preclinical and ongoing clinical trials, evidence of its efficacy against SARS-CoV-2 in COVID-19, side effects, anti-viral mechanism, and the pharmacokinetic properties of the drug in the treatment of COVID-19. Due to its teratogenic effects, favipiravir cannot be offered to expectant or pregnant mothers. The practical efficacy of such an intervention regimen will depend on its dose, treatment duration, and cost as well as difficulties in application.
Subject(s)
Asia , Communicable Disease Control/organization & administration , Health Policy , Health Promotion/organization & administration , Helminthiasis/prevention & control , Humans , International Agencies/organization & administration , Malaria/prevention & control , Parasitic Diseases/prevention & control , Program Evaluation , School Health Services/organization & administration , Staff Development/organization & administrationABSTRACT
A study of intervention solutions for the exhaust from 4 thermo-electrical kilns, from synthetic process of in NH3 and dust due to NPK fertilizer production was carried out to evaluate the efficacy of technological improvement solutions in reducing environment pollution. Results: concentration of dust and toxic fumes was reduced, concentration of the exhaust components eliminated to environment through the chimneys of gases-made kilns reduced significantly after changing technology. NH3, CH4, H2 from producing NH3 decreased clearly, dust from producing NPK reduced 1.63-1.92 times
Subject(s)
Environmental Pollution , Gases , Waste Products , FertilizersABSTRACT
The quality of drinking and running water had major influenced to human health. The use of comtanimated water could be cause of cholera, dysenteria, and typhoid outbreaks with different scales. Aside from many water-born diseases with the causes of microbilogy, chemical contamination also is a major threat for community health. So, it is necessary to strengthen control the quality of water by authorities and community
Subject(s)
Water , Health , Health Services , Residence CharacteristicsABSTRACT
The study surveyed the morbidity and hospital admission of Bac Giang city population in the year 2001, especially the prevalence of cancer. 3.000 households were enrolled in the study. Data were collected and interviews were conducted. Analysis showed people had a high demand of health care in hospital, especially with cancer management. 31.1% of urban population demanded a hospital admission. In 5 year period in the city, the cancer incidence was 158.9/100.000 people in average. The highest was in 50-69 age group, and this incidence was higher in male than female
Subject(s)
Therapeutics , Inpatients/epidemiology , Morbidity , EpidemiologyABSTRACT
To survey and assest the safe rational and effective use of antibiotics. The success and shortage in the use of C in the National hospital of Gynecology and Obstetrics. The management of antibiotic use in functional department of the hospital was subjected to a retrospective study using an interviewed questionary, comparative and analyzed investigation. Results showed some success in the safe, rational and effective use of antibiotics contributing significantly in improving efficiency and the cost :In addition, this helped to minish the antibiotic resistancy
Subject(s)
Anti-Bacterial Agents , Epidemiology , Drug Resistance, MicrobialABSTRACT
In this study, the contents of steroid hormones and micro-substances in 5 salt-water fishes including Sea-horse, White hering, Garrupa, Selachian and Mackerel were studied. The result demonstrated that: the contents of steroid hormones in 5 mentioned fishes were relatively higher than other salt-water creatures. The study also explored the availability as well as contents of some necessary micro-substances in these salt-water fishes (K, Ca, Cu, Fe, Zn, Mn, Se). Although, the ability of using the active elements in the 5 salt-water fishes as medicines to enhance health and prevent diseases is very potential, it needs further studies
ABSTRACT
The average incidence/case/year of Ha Bac nitrate and chemical factory during two years (2002-2003) was 1.38 incidence/case/year (2002) and 1.63 incidence/case/year (2003). The diseases were high incidence as follows: odonto-maxial-facial disease, ear-nose-throat disease. Workers with I health level and II health level were the highest: 70.33% (2002) and 65.05% (2003). The rate of workers with III health level were very high and tend to increase, remained the rate of workers with V health level.
Subject(s)
Health , Nitrates , Chemical IndustryABSTRACT
A retrospective study of 200 Kovacs has been applied in 2nd trimester abortion in 1997 and other 200 by MSP in 1998. -MSP could be efficacy in 2nd trimester abortion as Kovacs.-In first 48h, the natural abortion by MSP and Kovacs is the same.-The propotion of MSP abortion is higher than Kovacs, hospitalized stay length of MSP is shorter than Kovacs.-No infection in MSP trials